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The overall goals of our research program are to increase our understanding of the physiology and pathophysiology of the skin and, most importantly, to develop basic and clinical information leading to the development of new and improved treatments for diseases of the skin. The current active areas of research within the department include:
- Investigations on how environmental influences such as ultraviolet radiation inhibit immune processes within the skin, thus facilitating the development of skin cancer.
- Studies on defining the mechanisms by which the nervous system, psychology, and stress influence immunity within the skin.
- Studies on a novel form of soluble adenylyl cyclase (an important enzyme regulating aspects of cell biology) and its role in benign and malignant proliferations of the skin.
- Examination of derangements in immunity that allow skin cancers to escape immunologic control.
- Studies examining the mechanisms of action of novel anti-inflammatory agents and their utility for the treatment of inflammatory skin diseases.
These projects are funded by a mix of sources including the National Institutes of Health, private industry, foundations and contributions from individuals.